Resistance to cancer immunotherapy mediated by apoptosis of tumor-infiltrating lymphocytes

Despite impressive clinical success, cancer immunotherapy based on immune checkpoint blockade remains ineffective in many patients due to tumoral resistance. Here we use the autochthonous TiRP melanoma model, which recapitulates the tumoral resistance signature observed in human melanomas. TiRP tumo...

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Publicado en:Nat Commun
Main Authors: Zhu, Jingjing, Powis de Tenbossche, Céline G., Cané, Stefania, Colau, Didier, van Baren, Nicolas, Lurquin, Christophe, Schmitt-Verhulst, Anne-Marie, Liljeström, Peter, Uyttenhove, Catherine, Van den Eynde, Benoit J.
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group UK 2017
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5680273/
https://ncbi.nlm.nih.gov/pubmed/29123081
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-017-00784-1
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