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The matricellular protein CCN3 regulates NOTCH1 signalling in chronic myeloid leukaemia

Deregulated NOTCH1 has been reported in lymphoid leukaemia, although its role in chronic myeloid leukaemia (CML) is not well established. We previously reported BCR-ABL down-regulation of a novel haematopoietic regulator, CCN3, in CML; CCN3 is a non-canonical NOTCH1 ligand. This study characterizes...

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Detalhes bibliográficos
Publicado no:J Pathol
Main Authors: Suresh, Sukanya, McCallum, Lynn, Crawford, Lisa J, Lu, Wan Hua, Sharpe, Daniel J, Irvine, Alexandra E
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley & Sons, Ltd 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314772/
https://ncbi.nlm.nih.gov/pubmed/24308033
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/path.4246
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