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CCN3: a key growth regulator in Chronic Myeloid Leukaemia

Chronic Myeloid Leukaemia (CML) is characterized by expression of the constitutively active Bcr-Abl tyrosine kinase. We have shown previously that the negative growth regulator, CCN3, is down-regulated as a result of Bcr-Abl kinase activity and that CCN3 has a reciprocal relationship of expression w...

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Detalhes bibliográficos
Main Authors: McCallum, Lynn, Lu, Wanhua, Price, Susan, Lazar, Noureddine, Perbal, Bernard, Irvine, Alexandra E.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2721087/
https://ncbi.nlm.nih.gov/pubmed/19623482
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-009-0058-2
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