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MicroRNAs 130a/b are regulated by BCR-ABL and downregulate expression of CCN3 in CML

Chronic Myeloid Leukaemia (CML) is a myeloproliferative disorder characterized by the expression of the oncoprotein, Bcr-Abl kinase. CCN3 normally functions as a negative growth regulator, but it is downregulated in CML, the mechanism of which is not known. MicroRNAs (miRNAs) are small non-coding RN...

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Detalhes bibliográficos
Main Authors: Suresh, Sukanya, McCallum, Lynn, Lu, Wanhua, Lazar, Noureddine, Perbal, Bernard, Irvine, Alexandra E.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Netherlands 2011
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3145871/
https://ncbi.nlm.nih.gov/pubmed/21638198
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-011-0139-x
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