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MicroRNAs 130a/b are regulated by BCR-ABL and downregulate expression of CCN3 in CML
Chronic Myeloid Leukaemia (CML) is a myeloproliferative disorder characterized by the expression of the oncoprotein, Bcr-Abl kinase. CCN3 normally functions as a negative growth regulator, but it is downregulated in CML, the mechanism of which is not known. MicroRNAs (miRNAs) are small non-coding RN...
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Main Authors: | , , , , , |
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Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Springer Netherlands
2011
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3145871/ https://ncbi.nlm.nih.gov/pubmed/21638198 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12079-011-0139-x |
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