Chronic alcohol exposure exacerbates inflammation and triggers pancreatic acinar-to-ductal metaplasia through PI3K/Akt/IKK

Pancreatic acinar-to-ductal metaplasia (ADM) has been identified as an initiating event that can progress to pancreatic intraepithelial neoplasia (PanIN) or pancreatic ductal adenocarcinoma (PDAC). Acini transdifferentiation can be induced by persistent inflammation. Notably, compelling evidence has...

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Bibliografiska uppgifter
I publikationen:Int J Mol Med
Huvudupphovsmän: HUANG, XIN, LI, XUQI, MA, QINGYONG, XU, QINHONG, DUAN, WANXING, LEI, JIANJUN, ZHANG, LUN, WU, ZHENG
Materialtyp: Artigo
Språk:Inglês
Publicerad: D.A. Spandidos 2015
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314411/
https://ncbi.nlm.nih.gov/pubmed/25573338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2014.2055
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