Chronic alcohol exposure exacerbates inflammation and triggers pancreatic acinar-to-ductal metaplasia through PI3K/Akt/IKK

Pancreatic acinar-to-ductal metaplasia (ADM) has been identified as an initiating event that can progress to pancreatic intraepithelial neoplasia (PanIN) or pancreatic ductal adenocarcinoma (PDAC). Acini transdifferentiation can be induced by persistent inflammation. Notably, compelling evidence has...

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Bibliographic Details
Published in:Int J Mol Med
Main Authors: HUANG, XIN, LI, XUQI, MA, QINGYONG, XU, QINHONG, DUAN, WANXING, LEI, JIANJUN, ZHANG, LUN, WU, ZHENG
Format: Artigo
Language:Inglês
Published: D.A. Spandidos 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314411/
https://ncbi.nlm.nih.gov/pubmed/25573338
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ijmm.2014.2055
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