α-Mangostin Suppresses the Viability and Epithelial-Mesenchymal Transition of Pancreatic Cancer Cells by Downregulating the PI3K/Akt Pathway

α-Mangostin, a natural product isolated from the pericarp of the mangosteen fruit, has been shown to inhibit the growth of tumor cells in various types of cancers. However, the underlying molecular mechanisms are largely unclear. Here, we report that α-mangostin suppressed the viability and epitheli...

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Библиографические подробности
Главные авторы: Xu, Qinhong, Ma, Jiguang, Lei, Jianjun, Duan, Wanxing, Sheng, Liang, Chen, Xin, Hu, Ang, Wang, Zheng, Wu, Zheng, Wu, Erxi, Ma, Qingyong, Li, Xuqi
Формат: Artigo
Язык:Inglês
Опубликовано: Hindawi Publishing Corporation 2014
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Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000937/
https://ncbi.nlm.nih.gov/pubmed/24812621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/546353
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