α-Mangostin Suppresses the Viability and Epithelial-Mesenchymal Transition of Pancreatic Cancer Cells by Downregulating the PI3K/Akt Pathway

α-Mangostin, a natural product isolated from the pericarp of the mangosteen fruit, has been shown to inhibit the growth of tumor cells in various types of cancers. However, the underlying molecular mechanisms are largely unclear. Here, we report that α-mangostin suppressed the viability and epitheli...

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Detalhes bibliográficos
Main Authors: Xu, Qinhong, Ma, Jiguang, Lei, Jianjun, Duan, Wanxing, Sheng, Liang, Chen, Xin, Hu, Ang, Wang, Zheng, Wu, Zheng, Wu, Erxi, Ma, Qingyong, Li, Xuqi
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2014
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000937/
https://ncbi.nlm.nih.gov/pubmed/24812621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/546353
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