α-Mangostin Suppresses the Viability and Epithelial-Mesenchymal Transition of Pancreatic Cancer Cells by Downregulating the PI3K/Akt Pathway

α-Mangostin, a natural product isolated from the pericarp of the mangosteen fruit, has been shown to inhibit the growth of tumor cells in various types of cancers. However, the underlying molecular mechanisms are largely unclear. Here, we report that α-mangostin suppressed the viability and epitheli...

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Bibliografski detalji
Glavni autori: Xu, Qinhong, Ma, Jiguang, Lei, Jianjun, Duan, Wanxing, Sheng, Liang, Chen, Xin, Hu, Ang, Wang, Zheng, Wu, Zheng, Wu, Erxi, Ma, Qingyong, Li, Xuqi
Format: Artigo
Jezik:Inglês
Izdano: Hindawi Publishing Corporation 2014
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4000937/
https://ncbi.nlm.nih.gov/pubmed/24812621
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2014/546353
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