Hedgehog signaling regulates hypoxia induced epithelial to mesenchymal transition and invasion in pancreatic cancer cells via a ligand-independent manner

BACKGROUND: Hypoxia plays a vital role in cancer epithelial to mesenchymal transition (EMT) and invasion. However, it is not quite clear how hypoxia may contribute to these events. Here we investigate the role of Hedgehog (Hh) signaling in hypoxia induced pancreatic cancer EMT and invasion. METHODS:...

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Detaylı Bibliyografya
Asıl Yazarlar: Lei, Jianjun, Ma, Jiguang, Ma, Qingyong, Li, Xuqi, Liu, Han, Xu, Qinhong, Duan, Wanxing, Sun, Qing, Xu, Jun, Wu, Zheng, Wu, Erxi
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: BioMed Central 2013
Konular:
Research
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699387/
https://ncbi.nlm.nih.gov/pubmed/23786654
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-12-66
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