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Bidirectional enantioselective effects of the GABA(B) receptor agonist baclofen in two mouse models of excessive ethanol consumption

The GABA(B) receptor agonist baclofen has been studied extensively in preclinical models of alcohol use disorders, yet results on its efficacy have been uncertain. Racemic baclofen, which is used clinically, can be broken down into separate enantiomers of the drug. Baclofen has been shown to produce...

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Publicat a:Alcohol
Autors principals: Kasten, Chelsea R., Blasingame, Shelby N., Boehm, Stephen L.
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314367/
https://ncbi.nlm.nih.gov/pubmed/25557834
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.alcohol.2014.11.005
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