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Intra-nucleus accumbens shell injections of R(+)- and S(-)-baclofen bidirectionally alter binge-like ethanol, but not saccharin, intake in C57Bl/6J mice

The GABA(B) agonist baclofen has been widely researched clinically and preclinically as a treatment of alcohol use disorders (AUDs). However, the efficacy of baclofen remains uncertain. The clinically used racemic compound can be separated into separate enantiomers. These enantiomers have produced d...

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Hlavní autoři: Kasten, Chelsea R., Boehm, Stephen L.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4134668/
https://ncbi.nlm.nih.gov/pubmed/25026094
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbr.2014.07.011
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