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Rotigotine is a potent agonist at dopamine D(1) receptors as well as at dopamine D(2) and D(3) receptors

BACKGROUND AND PURPOSE: Rotigotine acts as a dopamine receptor agonist with high affinity for the dopamine D(2), D(3), D(4) and D(5) receptors but with a low affinity for the dopamine D(1) receptor. We have investigated this further in radioligand binding and functional studies and compared the prof...

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Detalhes bibliográficos
Publicado no:Br J Pharmacol
Main Authors: Wood, Martyn, Dubois, Vanessa, Scheller, Dieter, Gillard, Michel
Formato: Artigo
Idioma:Inglês
Publicado em: BlackWell Publishing Ltd 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4314200/
https://ncbi.nlm.nih.gov/pubmed/25339241
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bph.12988
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