(64)Cu antibody-targeting of the T-cell receptor and subsequent internalization enables in vivo tracking of lymphocytes by PET

T cells are key players in inflammation, autoimmune diseases, and immunotherapy. Thus, holistic and noninvasive in vivo characterizations of the temporal distribution and homing dynamics of lymphocytes in mammals are of special interest. Herein, we show that PET-based T-cell labeling facilitates qua...

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Dettagli Bibliografici
Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Griessinger, Christoph M., Maurer, Andreas, Kesenheimer, Christian, Kehlbach, Rainer, Reischl, Gerald, Ehrlichmann, Walter, Bukala, Daniel, Harant, Maren, Cay, Funda, Brück, Jürgen, Nordin, Renate, Kohlhofer, Ursula, Rammensee, Hans-Georg, Quintanilla-Martinez, Leticia, Schaller, Martin, Röcken, Martin, Pichler, Bernd J., Kneilling, Manfred
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
Soggetti:
Biological Sciences
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313850/
https://ncbi.nlm.nih.gov/pubmed/25587131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1418391112
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