(64)Cu antibody-targeting of the T-cell receptor and subsequent internalization enables in vivo tracking of lymphocytes by PET

T cells are key players in inflammation, autoimmune diseases, and immunotherapy. Thus, holistic and noninvasive in vivo characterizations of the temporal distribution and homing dynamics of lymphocytes in mammals are of special interest. Herein, we show that PET-based T-cell labeling facilitates qua...

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Detalhes bibliográficos
Publicado no:Proc Natl Acad Sci U S A
Main Authors: Griessinger, Christoph M., Maurer, Andreas, Kesenheimer, Christian, Kehlbach, Rainer, Reischl, Gerald, Ehrlichmann, Walter, Bukala, Daniel, Harant, Maren, Cay, Funda, Brück, Jürgen, Nordin, Renate, Kohlhofer, Ursula, Rammensee, Hans-Georg, Quintanilla-Martinez, Leticia, Schaller, Martin, Röcken, Martin, Pichler, Bernd J., Kneilling, Manfred
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2015
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313850/
https://ncbi.nlm.nih.gov/pubmed/25587131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1418391112
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