Preclinical evaluation of the anti-tumor effects of the natural isoflavone genistein in two xenograft mouse models monitored by [(18)F]FDG, [(18)F]FLT, and [(64)Cu]NODAGA-cetuximab small animal PET

The natural phytoestrogen genistein is known as protein kinase inhibitor and tumor suppressor in various types of cancers. We studied its antitumor effect in two different xenograft models using positron emission tomography (PET) in vivo combined with ex vivo histology and nuclear magnetic resonance...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Honndorf, Valerie S., Wiehr, Stefan, Rolle, Anna-Maria, Schmitt, Julia, Kreft, Luisa, Quintanilla-Martinez, Letitia, Kohlhofer, Ursula, Reischl, Gerald, Maurer, Andreas, Boldt, Karsten, Schwarz, Michael, Schmidt, Holger, Pichler, Bernd J.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053724/
https://ncbi.nlm.nih.gov/pubmed/27070087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8625
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