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Preclinical evaluation of the anti-tumor effects of the natural isoflavone genistein in two xenograft mouse models monitored by [(18)F]FDG, [(18)F]FLT, and [(64)Cu]NODAGA-cetuximab small animal PET

The natural phytoestrogen genistein is known as protein kinase inhibitor and tumor suppressor in various types of cancers. We studied its antitumor effect in two different xenograft models using positron emission tomography (PET) in vivo combined with ex vivo histology and nuclear magnetic resonance...

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Publicat a:Oncotarget
Autors principals: Honndorf, Valerie S., Wiehr, Stefan, Rolle, Anna-Maria, Schmitt, Julia, Kreft, Luisa, Quintanilla-Martinez, Letitia, Kohlhofer, Ursula, Reischl, Gerald, Maurer, Andreas, Boldt, Karsten, Schwarz, Michael, Schmidt, Holger, Pichler, Bernd J.
Format: Artigo
Idioma:Inglês
Publicat: Impact Journals LLC 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053724/
https://ncbi.nlm.nih.gov/pubmed/27070087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8625
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