Preclinical evaluation of the anti-tumor effects of the natural isoflavone genistein in two xenograft mouse models monitored by [(18)F]FDG, [(18)F]FLT, and [(64)Cu]NODAGA-cetuximab small animal PET

The natural phytoestrogen genistein is known as protein kinase inhibitor and tumor suppressor in various types of cancers. We studied its antitumor effect in two different xenograft models using positron emission tomography (PET) in vivo combined with ex vivo histology and nuclear magnetic resonance...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Honndorf, Valerie S., Wiehr, Stefan, Rolle, Anna-Maria, Schmitt, Julia, Kreft, Luisa, Quintanilla-Martinez, Letitia, Kohlhofer, Ursula, Reischl, Gerald, Maurer, Andreas, Boldt, Karsten, Schwarz, Michael, Schmidt, Holger, Pichler, Bernd J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2016
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5053724/
https://ncbi.nlm.nih.gov/pubmed/27070087
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.8625
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