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Genomic responses in mouse models greatly mimic human inflammatory diseases

The use of mice as animal models has long been considered essential in modern biomedical research, but the role of mouse models in research was challenged by a recent report that genomic responses in mouse models poorly mimic human inflammatory diseases. Here we reevaluated the same gene expression...

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Pubblicato in:Proc Natl Acad Sci U S A
Autori principali: Takao, Keizo, Miyakawa, Tsuyoshi
Natura: Artigo
Lingua:Inglês
Pubblicazione: National Academy of Sciences 2015
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313832/
https://ncbi.nlm.nih.gov/pubmed/25092317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1401965111
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