Humanized Mouse Model of Ebola Virus Disease Mimics the Immune Responses in Human Disease

Animal models recapitulating human Ebola virus disease (EVD) are critical for insights into virus pathogenesis. Ebola virus (EBOV) isolates derived directly from human specimens do not, without adaptation, cause disease in immunocompetent adult rodents. Here, we describe EVD in mice engrafted with h...

詳細記述

保存先:
書誌詳細
出版年:J Infect Dis
主要な著者: Bird, Brian H., Spengler, Jessica R., Chakrabarti, Ayan K., Khristova, Marina L., Sealy, Tara K., Coleman-McCray, JoAnn D., Martin, Brock E., Dodd, Kimberly A., Goldsmith, Cynthia S., Sanders, Jeanine, Zaki, Sherif R., Nichol, Stuart T., Spiropoulou, Christina F.
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2016
主題:
Major Articles and Brief Reports
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4747627/
https://ncbi.nlm.nih.gov/pubmed/26582961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiv538
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