Genomic responses in mouse models poorly mimic human inflammatory diseases

A cornerstone of modern biomedical research is the use of mouse models to explore basic pathophysiological mechanisms, evaluate new therapeutic approaches, and make go or no-go decisions to carry new drug candidates forward into clinical trials. Systematic studies evaluating how well murine models m...

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Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Seok, Junhee, Warren, H. Shaw, Cuenca, Alex G., Mindrinos, Michael N., Baker, Henry V., Xu, Weihong, Richards, Daniel R., McDonald-Smith, Grace P., Gao, Hong, Hennessy, Laura, Finnerty, Celeste C., López, Cecilia M., Honari, Shari, Moore, Ernest E., Minei, Joseph P., Cuschieri, Joseph, Bankey, Paul E., Johnson, Jeffrey L., Sperry, Jason, Nathens, Avery B., Billiar, Timothy R., West, Michael A., Jeschke, Marc G., Klein, Matthew B., Gamelli, Richard L., Gibran, Nicole S., Brownstein, Bernard H., Miller-Graziano, Carol, Calvano, Steve E., Mason, Philip H., Cobb, J. Perren, Rahme, Laurence G., Lowry, Stephen F., Maier, Ronald V., Moldawer, Lyle L., Herndon, David N., Davis, Ronald W., Xiao, Wenzhong, Tompkins, Ronald G., Abouhamze, Amer, Balis, Ulysses G. J., Camp, David G., De, Asit K., Harbrecht, Brian G., Hayden, Douglas L., Kaushal, Amit, O’Keefe, Grant E., Kotz, Kenneth T., Qian, Weijun, Schoenfeld, David A., Shapiro, Michael B., Silver, Geoffrey M., Smith, Richard D., Storey, John D., Tibshirani, Robert, Toner, Mehmet, Wilhelmy, Julie, Wispelwey, Bram, Wong, Wing H
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2013
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3587220/
https://ncbi.nlm.nih.gov/pubmed/23401516
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1222878110
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