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Genomic responses in mouse models greatly mimic human inflammatory diseases

The use of mice as animal models has long been considered essential in modern biomedical research, but the role of mouse models in research was challenged by a recent report that genomic responses in mouse models poorly mimic human inflammatory diseases. Here we reevaluated the same gene expression...

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Détails bibliographiques
Publié dans:Proc Natl Acad Sci U S A
Auteurs principaux: Takao, Keizo, Miyakawa, Tsuyoshi
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2015
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313832/
https://ncbi.nlm.nih.gov/pubmed/25092317
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1401965111
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