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Therapeutic Re-Activation of Protein Phosphatase 2A in Acute Myeloid Leukemia
Protein phosphatase 2A (PP2A) is a serine/threonine phosphatase that is required for normal cell growth and development. PP2A is a potent tumor suppressor, which is inactivated in cancer cells as a result of genetic deletions and mutations. In myeloid leukemias, genes encoding PP2A subunits are gene...
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| Publicado en: | Front Oncol |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Frontiers Media S.A.
2015
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4313608/ https://ncbi.nlm.nih.gov/pubmed/25699237 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2015.00016 |
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