A new regulatory mechanism of protein phosphatase 2A activity via SET in acute myeloid leukemia

Acute myeloid leukemia (AML) is an aggressive hematologic malignancy. Although novel emerging drugs are available, the overall prognosis remains poor and new therapeutic approaches are required. PP2A phosphatase is a key regulator of cell homeostasis and is recurrently inactivated in AML. The antica...

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Vydáno v:Blood Cancer J
Hlavní autoři: Arriazu, Elena, Vicente, Carmen, Pippa, Raffaella, Peris, Irene, Martínez-Balsalobre, Elena, García-Ramírez, Patricia, Marcotegui, Nerea, Igea, Ana, Alignani, Diego, Rifón, José, Mateos, María C., Cayuela, María L., Nebreda, Angel R., Odero, María D.
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2020
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Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6949222/
https://ncbi.nlm.nih.gov/pubmed/31913266
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41408-019-0270-0
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