Targeting Bcl-2 Proteins in Acute Myeloid Leukemia

B cell lymphoma 2 (BCL-2) family proteins play an important role in intrinsic apoptosis. Overexpression of BCL-2 proteins in acute myeloid leukemia can circumvent resistance to apoptosis and chemotherapy. Considering this effect, the exploration of anti-apoptotic BCL-2 inhibitors is considered to ha...

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Detalhes bibliográficos
Publicado no:Front Oncol
Main Authors: Wei, Yunxiong, Cao, Yaqing, Sun, Rui, Cheng, Lin, Xiong, Xia, Jin, Xin, He, Xiaoyuan, Lu, Wenyi, Zhao, Mingfeng
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2020
Assuntos:
Oncology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7674767/
https://ncbi.nlm.nih.gov/pubmed/33251145
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2020.584974
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