Infection Temperature Affects the Phenotype and Function of Chimeric Antigen Receptor T Cells Produced via Lentiviral Technology

Chimeric antigen receptor (CAR)-T cell therapy has become an important method for the treatment of hematological tumors. Lentiviruses are commonly used gene transfer vectors for preparing CAR-T cells, and the conditions for preparing CAR-T cells vary greatly. This study reported for the first time t...

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Publicado en:Front Immunol
Autores principales: Jin, Xin, Lu, Wenyi, Zhang, Meng, Xiong, Xia, Sun, Rui, Wei, Yunxiong, He, Xiaoyuan, Zhao, Mingfeng
Formato: Artigo
Lenguaje:Inglês
Publicado: Frontiers Media S.A. 2021
Materias:
Immunology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC8089475/
https://ncbi.nlm.nih.gov/pubmed/33953713
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2021.638907
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