BMP-2, Hypoxia, and COL1A1/HtrA1 siRNAs Favor Neo-Cartilage Hyaline Matrix Formation in Chondrocytes

Osteoarthritis (OA) is an irreversible pathology that causes a decrease in articular cartilage thickness, leading finally to the complete degradation of the affected joint. The low spontaneous repair capacity of cartilage prevents any restoration of the joint surface, making OA a major public health...

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Bibliographic Details
Published in:Tissue Eng Part C Methods
Main Authors: Ollitrault, David, Legendre, Florence, Drougard, Carole, Briand, Mélanie, Benateau, Hervé, Goux, Didier, Chajra, Hanane, Poulain, Laurent, Hartmann, Daniel, Vivien, Denis, Shridhar, Vijayalakshmi, Baldi, Alfonso, Mallein-Gerin, Frédéric, Boumediene, Karim, Demoor, Magali, Galera, Philippe
Format: Artigo
Language:Inglês
Published: Mary Ann Liebert, Inc. 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4313417/
https://ncbi.nlm.nih.gov/pubmed/24957638
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1089/ten.tec.2013.0724
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