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Liposomal vaccines incorporating molecular adjuvants and intrastructural T-cell help promote the immunogenicity of HIV membrane-proximal external region peptides

An HIV vaccine capable of inducing high and durable levels of broadly neutralizing antibodies has thus far proven elusive. A promising antigen is the membrane-proximal external region (MPER) from gp41, a segment of the viral envelope recognized by a number of broadly neutralizing antibodies. Though...

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Publicat a:Vaccine
Autors principals: Hanson, Melissa C., Abraham, Wuhbet, Crespo, Monica P., Chen, Stephanie H., Liu, Haipeng, Szeto, Greg Lee, Kim, Mikyung, Reinherz, Ellis L., Irvine, Darrell J.
Format: Artigo
Idioma:Inglês
Publicat: 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312707/
https://ncbi.nlm.nih.gov/pubmed/25559188
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2014.12.045
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