Toxicity and immunogenicity of Neisseria meningitidis lipopolysaccharide incorporated into liposomes.

To obtain nontoxic and highly immunogenic lipopolysaccharide (LPS) for immunization, we incorporated Neisseria meningitidis LPS into liposomes. Native LPS and its salts were incorporated by the method of dehydration-rehydration of vesicles or prolonged cosonication. The most complete incorporation o...

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Detalhes bibliográficos
Main Authors: Petrov, A B, Semenov, B F, Vartanyan, Y P, Zakirov, M M, Torchilin, V P, Trubetskoy, V S, Koshkina, N V, L'Vov, V L, Verner, I K, Lopyrev, I V
Formato: Artigo
Idioma:Inglês
Publicado em: 1992
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC257405/
https://ncbi.nlm.nih.gov/pubmed/1500196
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