Toxicity and immunogenicity of Neisseria meningitidis lipopolysaccharide incorporated into liposomes.

To obtain nontoxic and highly immunogenic lipopolysaccharide (LPS) for immunization, we incorporated Neisseria meningitidis LPS into liposomes. Native LPS and its salts were incorporated by the method of dehydration-rehydration of vesicles or prolonged cosonication. The most complete incorporation o...

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Enregistré dans:
Détails bibliographiques
Auteurs principaux: Petrov, A B, Semenov, B F, Vartanyan, Y P, Zakirov, M M, Torchilin, V P, Trubetskoy, V S, Koshkina, N V, L'Vov, V L, Verner, I K, Lopyrev, I V
Format: Artigo
Langue:Inglês
Publié: 1992
Sujets:
Research Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC257405/
https://ncbi.nlm.nih.gov/pubmed/1500196
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