Toxicity and immunogenicity of Neisseria meningitidis lipopolysaccharide incorporated into liposomes.

To obtain nontoxic and highly immunogenic lipopolysaccharide (LPS) for immunization, we incorporated Neisseria meningitidis LPS into liposomes. Native LPS and its salts were incorporated by the method of dehydration-rehydration of vesicles or prolonged cosonication. The most complete incorporation o...

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Bibliografische gegevens
Gepubliceerd in:Infect Immun
Hoofdauteurs: Petrov, A B, Semenov, B F, Vartanyan, Y P, Zakirov, M M, Torchilin, V P, Trubetskoy, V S, Koshkina, N V, L'Vov, V L, Verner, I K, Lopyrev, I V
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: American Society for Microbiology (ASM) 1992
Onderwerpen:
Research Article
Online toegang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257405/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1500196/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.9.3897-3903.1992
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