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Toxicity and immunogenicity of Neisseria meningitidis lipopolysaccharide incorporated into liposomes.

To obtain nontoxic and highly immunogenic lipopolysaccharide (LPS) for immunization, we incorporated Neisseria meningitidis LPS into liposomes. Native LPS and its salts were incorporated by the method of dehydration-rehydration of vesicles or prolonged cosonication. The most complete incorporation o...

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Bibliografiske detaljer
Udgivet i:Infect Immun
Principais autores: Petrov, A B, Semenov, B F, Vartanyan, Y P, Zakirov, M M, Torchilin, V P, Trubetskoy, V S, Koshkina, N V, L'Vov, V L, Verner, I K, Lopyrev, I V
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 1992
Fag:
Online adgang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC257405/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/1500196/
https://ncbi.nlm.nih.govhttps://doi.org/10.1128/iai.60.9.3897-3903.1992
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