Myosin-II controls cellular branching morphogenesis and migration in 3D by minimizing cell surface curvature

In many cases cell function is intimately linked to cell shape control. We utilized endothelial cell branching morphogenesis as a model to understand the role of myosin-II in shape control of invasive cells migrating in 3D collagen gels. We applied principles of differential geometry and mathematica...

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Bibliografske podrobnosti
izdano v:Nat Cell Biol
Main Authors: Elliott, Hunter, Fischer, Robert A., Myers, Kenneth A., Desai, Ravi A., Gao, Lin, Chen, Christopher S., Adelstein, Robert, Waterman, Clare M., Danuser, Gaudenz
Format: Artigo
Jezik:Inglês
Izdano: 2015
Teme:
Article
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312523/
https://ncbi.nlm.nih.gov/pubmed/25621949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3092
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