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Myosin-II controls cellular branching morphogenesis and migration in 3D by minimizing cell surface curvature

In many cases cell function is intimately linked to cell shape control. We utilized endothelial cell branching morphogenesis as a model to understand the role of myosin-II in shape control of invasive cells migrating in 3D collagen gels. We applied principles of differential geometry and mathematica...

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Библиографические подробности
Опубликовано в: :Nat Cell Biol
Главные авторы: Elliott, Hunter, Fischer, Robert A., Myers, Kenneth A., Desai, Ravi A., Gao, Lin, Chen, Christopher S., Adelstein, Robert, Waterman, Clare M., Danuser, Gaudenz
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312523/
https://ncbi.nlm.nih.gov/pubmed/25621949
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3092
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