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Myosin II mediates local cortical tension to guide endothelial cell branching morphogenesis and migration in 3D

A key feature of angiogenesis is directional control of endothelial cell (EC) morphogenesis and movement [1]. During angiogenic sprouting, endothelial “tip cells” directionally branch from existing vessels in response to biochemical cues such as VEGF or hypoxia, and migrate and invade the surroundin...

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Bibliografiska uppgifter
Huvudupphovsmän: Fischer, Robert S., Gardel, Margaret, Ma, Xuefei, Adelstein, Robert, Waterman, Clare M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2009
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2777763/
https://ncbi.nlm.nih.gov/pubmed/19185493
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2008.12.045
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