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Pak1 regulates focal adhesion strength, myosin IIA distribution, and actin dynamics to optimize cell migration

Cell motility requires the spatial and temporal coordination of forces in the actomyosin cytoskeleton with extracellular adhesion. The biochemical mechanism that coordinates filamentous actin (F-actin) assembly, myosin contractility, adhesion dynamics, and motility to maintain the balance between ad...

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Detalles Bibliográficos
Main Authors: Delorme-Walker, Violaine D., Peterson, Jeffrey R., Chernoff, Jonathan, Waterman, Clare M., Danuser, Gaudenz, DerMardirossian, Céline, Bokoch, Gary M.
Formato: Artigo
Idioma:Inglês
Publicado: The Rockefeller University Press 2011
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216326/
https://ncbi.nlm.nih.gov/pubmed/21708980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201010059
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