Pak1 regulates focal adhesion strength, myosin IIA distribution, and actin dynamics to optimize cell migration

Cell motility requires the spatial and temporal coordination of forces in the actomyosin cytoskeleton with extracellular adhesion. The biochemical mechanism that coordinates filamentous actin (F-actin) assembly, myosin contractility, adhesion dynamics, and motility to maintain the balance between ad...

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Bibliografske podrobnosti
Main Authors: Delorme-Walker, Violaine D., Peterson, Jeffrey R., Chernoff, Jonathan, Waterman, Clare M., Danuser, Gaudenz, DerMardirossian, Céline, Bokoch, Gary M.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2011
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216326/
https://ncbi.nlm.nih.gov/pubmed/21708980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201010059
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