Intestinal epithelial vitamin D receptor deletion leads to defective autophagyin colitis

OBJECTIVE: Vitamin D and the vitamin D receptor (VDR) appear to be important immunological regulators of inflammatory bowel diseases (IBD). Defective autophagy has also been implicated in IBD, where interestingly, polymorphisms of genes such as ATG16L1 have been associated with increased risk. Altho...

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Bibliographische Detailangaben
Veröffentlicht in:Gut
Hauptverfasser: Wu, Shaoping, Zhang, Yong-guo, Lu, Rong, Xia, Yinglin, Zhou, David, Petrof, Elaine, Claud, Erika C, Chen, Di, Chang, Eugene B, Carmeliet, Geert, Sun, Jun
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312277/
https://ncbi.nlm.nih.gov/pubmed/25080448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2014-307436
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