Intestinal epithelial vitamin D receptor deletion leads to defective autophagyin colitis

OBJECTIVE: Vitamin D and the vitamin D receptor (VDR) appear to be important immunological regulators of inflammatory bowel diseases (IBD). Defective autophagy has also been implicated in IBD, where interestingly, polymorphisms of genes such as ATG16L1 have been associated with increased risk. Altho...

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Bibliografiske detaljer
Udgivet i:Gut
Main Authors: Wu, Shaoping, Zhang, Yong-guo, Lu, Rong, Xia, Yinglin, Zhou, David, Petrof, Elaine, Claud, Erika C, Chen, Di, Chang, Eugene B, Carmeliet, Geert, Sun, Jun
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312277/
https://ncbi.nlm.nih.gov/pubmed/25080448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2014-307436
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