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Intestinal epithelial vitamin D receptor deletion leads to defective autophagyin colitis

OBJECTIVE: Vitamin D and the vitamin D receptor (VDR) appear to be important immunological regulators of inflammatory bowel diseases (IBD). Defective autophagy has also been implicated in IBD, where interestingly, polymorphisms of genes such as ATG16L1 have been associated with increased risk. Altho...

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Detalhes bibliográficos
Publicado no:Gut
Main Authors: Wu, Shaoping, Zhang, Yong-guo, Lu, Rong, Xia, Yinglin, Zhou, David, Petrof, Elaine, Claud, Erika C, Chen, Di, Chang, Eugene B, Carmeliet, Geert, Sun, Jun
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4312277/
https://ncbi.nlm.nih.gov/pubmed/25080448
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2014-307436
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