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Protein-Bound Uremic Toxins Induce Tissue Remodeling by Targeting the EGF Receptor

Indoxyl sulfate and p-cresol sulfate have been suggested to induce kidney tissue remodeling. This study aimed to clarify the molecular mechanisms underlying this tissue remodeling using cultured human proximal renal tubular cells and half-nephrectomized mice treated with indoxyl sulfate or p-cresol...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
הוצא לאור ב:J Am Soc Nephrol
Main Authors: Sun, Chiao-Yin, Young, Guang-Huar, Hsieh, Yu-Ting, Chen, Yau-Hung, Wu, Mai-Szu, Wu, Vin-Cent, Lee, Jia-Hung, Lee, Chin-Chan
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society of Nephrology 2015
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310659/
https://ncbi.nlm.nih.gov/pubmed/25012179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014010021
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