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Protein-bound uremic toxins impaired mitochondrial dynamics and functions

Protein-bound uremic toxins, indoxyl sulfate and p-cresol sulfate, increase oxidative stress and adversely affect chronic kidney disease progression and cardiovascular complications. In this study, we examined whether mitochondria are the target of indoxyl sulfate and p-cresol sulfate intoxication i...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Sun, Chiao-Yin, Cheng, Mei-Ling, Pan, Heng-Chih, Lee, Jia-Hung, Lee, Chin-Chan
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5652810/
https://ncbi.nlm.nih.gov/pubmed/29100420
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.20773
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