Protein-Bound Uremic Toxins Induce Tissue Remodeling by Targeting the EGF Receptor

Indoxyl sulfate and p-cresol sulfate have been suggested to induce kidney tissue remodeling. This study aimed to clarify the molecular mechanisms underlying this tissue remodeling using cultured human proximal renal tubular cells and half-nephrectomized mice treated with indoxyl sulfate or p-cresol...

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Sparad:
Bibliografiska uppgifter
I publikationen:J Am Soc Nephrol
Huvudupphovsmän: Sun, Chiao-Yin, Young, Guang-Huar, Hsieh, Yu-Ting, Chen, Yau-Hung, Wu, Mai-Szu, Wu, Vin-Cent, Lee, Jia-Hung, Lee, Chin-Chan
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society of Nephrology 2015
Ämnen:
Brief Communications
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310659/
https://ncbi.nlm.nih.gov/pubmed/25012179
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2014010021
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