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Uremic Toxins Induce Kidney Fibrosis by Activating Intrarenal Renin–Angiotensin–Aldosterone System Associated Epithelial-to-Mesenchymal Transition

BACKGROUND: Uremic toxins are considered to have a determinant pathological role in the progression of chronic kidney disease. The aim of this study was to define the putative pathological roles of the renal renin–angiotensin–aldosterone system (RAAS) and renal tubular epithelial-to-mesenchymal tran...

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Autori principali: Sun, Chiao-Yin, Chang, Shih-Chung, Wu, Mai-Szu
Natura: Artigo
Lingua:Inglês
Pubblicazione: Public Library of Science 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316590/
https://ncbi.nlm.nih.gov/pubmed/22479508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034026
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