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Uremic Toxins Induce Kidney Fibrosis by Activating Intrarenal Renin–Angiotensin–Aldosterone System Associated Epithelial-to-Mesenchymal Transition

BACKGROUND: Uremic toxins are considered to have a determinant pathological role in the progression of chronic kidney disease. The aim of this study was to define the putative pathological roles of the renal renin–angiotensin–aldosterone system (RAAS) and renal tubular epithelial-to-mesenchymal tran...

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Bibliografische gegevens
Hoofdauteurs: Sun, Chiao-Yin, Chang, Shih-Chung, Wu, Mai-Szu
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Public Library of Science 2012
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3316590/
https://ncbi.nlm.nih.gov/pubmed/22479508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0034026
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