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The Direct Assignment Option as a Modular Design Component: An Example for the Setting of Two Predefined Subgroups
Background. A phase II design with an option for direct assignment (stop randomization and assign all patients to experimental treatment based on interim analysis, IA) for a predefined subgroup was previously proposed. Here, we illustrate the modularity of the direct assignment option by applying it...
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| Udgivet i: | Comput Math Methods Med |
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| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Hindawi Publishing Corporation
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4310446/ https://ncbi.nlm.nih.gov/pubmed/25649690 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2015/210817 |
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