Nodal signaling promotes a tumorigenic phenotype in human breast cancer

The Ras-ERK pathway is deregulated in approximately a third of human cancers, particularly those of epithelial origin. In aggressive, triple-negative, basal-like breast cancers, most tumors display increased MEK and ERK phosphorylation and exhibit a gene expression profile characteristic of Kras or...

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Publicado en:Semin Cancer Biol
Main Authors: Kirsammer, Gina, Strizzi, Luigi, Margaryan, Naira V., Gilgur, Alina, Hyser, Matthew, Atkinson, Janis, Kirschmann, Dawn A., Seftor, Elisabeth A., Hendrix, Mary J.C.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4310244/
https://ncbi.nlm.nih.gov/pubmed/25073112
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semcancer.2014.07.007
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