Nodal as a biomarker for melanoma progression and a new therapeutic target for clinical intervention

Nodal, an embryonic morphogen belonging to the TGF-β superfamily, is an important regulator of embryonic stem cell fate. We have recently demonstrated that Nodal is expressed significantly in aggressive melanoma. Surprisingly, expression of the Nodal coreceptor, Cripto-1, was detected in only a smal...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Strizzi, Luigi, Postovit, Lynne-Marie, Margaryan, Naira V, Lipavsky, Alina, Gadiot, Jules, Blank, Christian, Seftor, Richard EB, Seftor, Elisabeth A, Hendrix, Mary JC
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2009
Pynciau:
Article
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2682534/
https://ncbi.nlm.nih.gov/pubmed/19885369
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1586/17469872.4.1.67
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