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Regulation of the embryonic morphogen Nodal by Notch4 facilitates manifestation of the aggressive melanoma phenotype

Metastatic melanoma is an aggressive skin cancer associated with poor prognosis. The reactivation of the embryonic morphogen Nodal in metastatic melanoma has previously been shown to regulate the aggressive behavior of these tumor cells. During the establishment of left-right asymmetry in early vert...

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Hlavní autoři: Hardy, Katharine M., Kirschmann, Dawn A., Seftor, Elisabeth A., Margaryan, Naira V., Postovit, Lynne-Marie, Strizzi, Luigi, Hendrix, Mary J.C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2010
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3057934/
https://ncbi.nlm.nih.gov/pubmed/21159651
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-10-0705
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