Human embryonic stem cell microenvironment suppresses the tumorigenic phenotype of aggressive cancer cells

Embryonic stem cells sustain a microenvironment that facilitates a balance of self-renewal and differentiation. Aggressive cancer cells, expressing a multipotent, embryonic cell-like phenotype, engage in a dynamic reciprocity with a microenvironment that promotes plasticity and tumorigenicity. Howev...

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Detalhes bibliográficos
Main Authors: Postovit, Lynne-Marie, Margaryan, Naira V., Seftor, Elisabeth A., Kirschmann, Dawn A., Lipavsky, Alina, Wheaton, William W., Abbott, Daniel E., Seftor, Richard E. B., Hendrix, Mary J. C.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2008
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2393795/
https://ncbi.nlm.nih.gov/pubmed/18334633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800467105
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