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Human embryonic stem cell microenvironment suppresses the tumorigenic phenotype of aggressive cancer cells
Embryonic stem cells sustain a microenvironment that facilitates a balance of self-renewal and differentiation. Aggressive cancer cells, expressing a multipotent, embryonic cell-like phenotype, engage in a dynamic reciprocity with a microenvironment that promotes plasticity and tumorigenicity. Howev...
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| Autori principali: | , , , , , , , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
National Academy of Sciences
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2393795/ https://ncbi.nlm.nih.gov/pubmed/18334633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0800467105 |
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