Gut Symbionts from Distinct Hosts Exhibit Genotoxic Activity via Divergent Colibactin Biosynthesis Pathways

Secondary metabolites produced by nonribosomal peptide synthetase (NRPS) or polyketide synthase (PKS) pathways are chemical mediators of microbial interactions in diverse environments. However, little is known about their distribution, evolution, and functional roles in bacterial symbionts associate...

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Bibliographic Details
Published in:Appl Environ Microbiol
Main Authors: Engel, Philipp, Vizcaino, Maria I., Crawford, Jason M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2015
Subjects:
Genetics and Molecular Biology
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309719/
https://ncbi.nlm.nih.gov/pubmed/25527542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.03283-14
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