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Gut Symbionts from Distinct Hosts Exhibit Genotoxic Activity via Divergent Colibactin Biosynthesis Pathways

Secondary metabolites produced by nonribosomal peptide synthetase (NRPS) or polyketide synthase (PKS) pathways are chemical mediators of microbial interactions in diverse environments. However, little is known about their distribution, evolution, and functional roles in bacterial symbionts associate...

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Detalhes bibliográficos
Publicado no:Appl Environ Microbiol
Main Authors: Engel, Philipp, Vizcaino, Maria I., Crawford, Jason M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309719/
https://ncbi.nlm.nih.gov/pubmed/25527542
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AEM.03283-14
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