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Comparative Metabolomics and Structural Characterizations Illuminate Colibactin Pathway-Dependent Small Molecules

[Image: see text] The gene cluster responsible for synthesis of the unknown molecule “colibactin” has been identified in mutualistic and pathogenic Escherichia coli. The pathway endows its producer with a long-term persistence phenotype in the human bowel, a probiotic activity used in the treatment...

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Detalhes bibliográficos
Main Authors: Vizcaino, Maria I., Engel, Philipp, Trautman, Eric, Crawford, Jason M.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4091280/
https://ncbi.nlm.nih.gov/pubmed/24932672
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja503450q
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