Murine Pancreatic Adenocarcinoma Reduces Ikaros Expression and Disrupts T Cell Homeostasis

BACKGROUND: Maintenance of T cell immune homeostasis is critical for adequate anti-tumor immunity. The transcription factor Ikaros is essential for lymphocyte development including T cells. Alterations in Ikaros expression occur in blood malignancies in humans and mice. In this study, we investigate...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:PLoS One
Autores principales: Nelson, Nadine, Xiang, Shengyan, Zhang, Xiaohong, Gilvary, Danielle, Djeu, Julie, Husain, Kazim, Malafa, Mokenge, Vohra, Nasreen, Pilon-Thomas, Shari, Ghansah, Tomar
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2015
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309586/
https://ncbi.nlm.nih.gov/pubmed/25629611
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0115546
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares