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Inhibition of Theiler’s Virus-Induced Apoptosis in Infected Murine Macrophages Results in Necroptosis

In mice Theiler’s murine encephalomyelitis virus (TMEV) persists in macrophages that eventually undergo apoptosis. TMEV infection of macrophages in culture induces apoptosis through the intrinsic pathway, restricting virus yields. We show that inhibition of TMEV-induced apoptosis leads to phosphoryl...

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Detalhes bibliográficos
Publicado no:Virus Res
Main Authors: Son, Kyung-No, Lipton, Howard L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4309367/
https://ncbi.nlm.nih.gov/pubmed/25449910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2014.10.017
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