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Activation of Tumor Suppressor Protein p53 Is Required for Theiler's Murine Encephalomyelitis Virus-Induced Apoptosis in M1-D Macrophages

Theiler's murine encephalomyelitis virus (TMEV) is a highly cytolytic picornavirus that persists in the mouse central nervous system (CNS) largely in macrophages with infection maintained by macrophage-to-macrophage spread. Infected macrophages in the CNS undergo apoptosis. We recently showed t...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Son, Kyung-No, Pugazhenthi, Subbiah, Lipton, Howard L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology (ASM) 2009
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2753135/
https://ncbi.nlm.nih.gov/pubmed/19656889
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01030-09
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