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Mutation of the Theiler’s virus leader protein zinc-finger domain impairs apoptotic activity in murine macrophages

The Theiler’s murine encephalomyelitis virus (TMEV) leader (L) protein zinc-finger domain was mutated to study its role in cell death in infection of the murine macrophage cell line M1-D, revealing that an intact zinc-finger domain is required for full apoptotic activity. A functional L zinc-finger...

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Bibliographic Details
Published in:Virus Res
Main Authors: Son, Kyung-No, Liang, Zhiguo, Lipton, Howard L.
Format: Artigo
Language:Inglês
Published: 2013
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4267530/
https://ncbi.nlm.nih.gov/pubmed/24036175
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2013.09.001
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