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Mutation of the Theiler’s virus leader protein zinc-finger domain impairs apoptotic activity in murine macrophages
The Theiler’s murine encephalomyelitis virus (TMEV) leader (L) protein zinc-finger domain was mutated to study its role in cell death in infection of the murine macrophage cell line M1-D, revealing that an intact zinc-finger domain is required for full apoptotic activity. A functional L zinc-finger...
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Publicado no: | Virus Res |
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Main Authors: | , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
2013
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4267530/ https://ncbi.nlm.nih.gov/pubmed/24036175 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.virusres.2013.09.001 |
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